Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Aftertreated polymer
Patent
1997-09-19
1999-12-28
Clardy, S. Mark
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Aftertreated polymer
424 7812, 424 7814, 424 7815, 424 7816, A61K 31785
Patent
active
060078030
ABSTRACT:
A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.
REFERENCES:
patent: 3929991 (1975-12-01), Steward et al.
patent: 4005193 (1977-01-01), Green et al.
patent: 4025617 (1977-05-01), Green et al.
patent: 4026945 (1977-05-01), Green et al.
patent: 4035480 (1977-07-01), Green et al.
patent: 4407791 (1983-10-01), Stark
patent: 4505926 (1985-03-01), Newsome et al.
patent: 4532128 (1985-07-01), Sheldon et al.
patent: 4604404 (1986-08-01), Munson, Jr. et al.
patent: 4621120 (1986-11-01), Hollister
patent: 4826924 (1989-05-01), Kourai et al.
patent: 5149524 (1992-09-01), Sherba et al.
patent: 5250293 (1993-10-01), Gleich
patent: 5498409 (1996-03-01), Hirayama et al.
Haynie, S. L., et al., "Antimicrobial Activities of Amphiphilic Peptides Covalently Bonded to a Water-Insoluble Resin", Antimicrob. Agents Chemotherapy, 39(2): 301-307 (1995).
Maloy, W. L. and Kari, U. P., "Structure-Activity Studies on Magainins and Other Host Defense Peptides", Biopolymers (Peptide Science) 37: 105-122 (1995).
Arrowood, M. J., et al., "Hemolytic Properties of Lytic Peptides Active Against the Sporozoites of Cryptosporidium parvum", J. Protozool.38(6): 161S-163S (1991).
Mammen, M., et al., "Effective Inhibitors of Hemagglutination by Influenza Virus Synthesized from Polymers Having Active Ester Groups. Insight into Mechanism of Inhibition," J. Med. Chem. (38) :4179-4190 (1995).
Zlochevskaya, I.V., et al., "Effect of Polyethyleneimine on Certain Fungi," Mosk. Univ. Biol. Sci. Bull. 30(3-4) :49-52 (1975).
Zalesov, V.S., et al., "Study of the Toxicity Physiological Effect and Antibacterial Activity of Polyethyleneimine," Nauchn. Tr. Permsk. Farm. Instit. (4) :31-35 (1971). Abstract.
Tashiro, T., "Removal of Escherichia coli from Water by Systems Based on Insoluble Polystyrene-Poly(ethylene Glycol)s,--Polyethylenimines, and -Polyethylenepolyamines Quaternized,"J. Polymer Sci. (34) :1369-1377 (1991).
Mandeville, III W. Harry
Neenan Thomas X.
Clardy S. Mark
GelTex Pharmaceuticals Inc.
Shelborne Kathryne E.
LandOfFree
Ionic polymers as toxin binding agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Ionic polymers as toxin binding agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ionic polymers as toxin binding agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2380421