Ionic enhanced dialysis/diafiltration system

Details Ionic enhanced dialysis/diafiltration system Ionic enhanced dialysis/diafiltration system

2006-06-27

2006-06-27

Kim, John (Department: 1723)

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

C210S257200, C210S321600, C210S321710, C210S321720, C210S433100, C210S645000, C210S647000

Reexamination Certificate

active

07067060

ABSTRACT:
A dual-stage system and methods for using the same include first and second filtration cartridges is provided and is particularly suited for hemodiafiltration and/or hemodialysis. As fluid enters the first filtration cartridge, the hydroxyl ion concentration and hence pH is increased by exposing it to either a strong base or a salt of a weak acid across a filter membrane. This stage allows for improved removal of certain toxins in the fluid, such as protein-bound substances that disassociate more readily from proteins at higher pH. As the filtered fluid enters the second filtration cartridge, the pH of the fluid is restored to normal levels prior to infusion to a patient.

REFERENCES:
patent: 5194157 (1993-03-01), Ghezzi et al.
patent: 5660722 (1997-08-01), Nederlof
patent: 5744042 (1998-04-01), Strange et al.
patent: 6406631 (2002-06-01), Collins et al.
patent: 6526357 (2003-02-01), Soussan et al.
patent: 6821431 (2004-11-01), Collins et al.
Copy of European Search Report for PCT/US01/01023.

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