Ionic 5-C-substituted 2,4,6-triiodoisophthalic acid derivatives

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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562442, 560 65, 562 37, 26050116, 26050111, 544107, 430967, A61K 4904, C07C 6308, C07C 6310

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active

043282024

ABSTRACT:
Ionic compounds of the formula ##STR1## wherein X is --CONR.sub.1 R.sub.2, --CH.sub.2 NH.multidot.Acyl or --CH.sub.2 OH; Y is --NR.sub.3 R.sub.4, --NH.multidot.Acyl or OR.sub.5 ; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 can be identical or different, and each is hydrogen, C.sub.1-6 - alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, R.sub.5 is C.sub.1-6 alkyl or C.sub.2-8 -alkyl substituted by 1-5 OH groups and/or by one C.sub.1-3 -alkoxy group, and Acyl, which can be the same or different in X and Y, is C.sub.2-6 -alkanoyl or C.sub.2-6 -alkanoyl substituted by 1-4 OH groups and/or by one C.sub.1-3 -alkoxy group, or a physiologically compatible salt thereof with an inorganic or organic base, have valuable properties as X-ray contrast agents.

REFERENCES:
patent: 3622616 (1971-11-01), Gverbet et al.
patent: 3819821 (1974-06-01), Tilly
patent: 4107286 (1978-08-01), Tilly et al.

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