Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2001-09-28
2011-10-11
Chong, Yong (Department: 1627)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S474000, C424S484000
Reexamination Certificate
active
08034379
ABSTRACT:
The present invention is related to an optionally coated pharmaceutical hydrophilic gel forming matrix formulation comprising one or more active substances and having a prolonged release of said one or more active substances upon exposure to gastrointestinal fluids, characterized in that said release is substantially ion-strength independent. The invention is further related to a method of preparing this formulation which can be used in the administration of active substances for the treatment of a large number of disorders.
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Pillay, V. et al., Electrolyte-Induced Compositional Heterogeneity: A Novel Approach for Rate-Controlled Oral Drug Delivery, Journal of Pharmaceutical Sciences, vol. 88, No. 11, pp. 1140-1148, Nov. 1999.
International Search Report for PCT/EP01/11285.
Frijlink Henderik W.
Gorissen Henricus R. M.
Chong Yong
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Solvay Pharmaceuticals B.V.
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