Ion source frequency feedback device and method

Radiant energy – Ionic separation or analysis – With sample supply means

Reexamination Certificate

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C250S42300F

Reexamination Certificate

active

07022982

ABSTRACT:
An ion source for an analytical instrument is described. The ion source comprises a capillary tip and counter-electrode interface and a feedback loop control device connected to the capillary tip and counter-electrode interface. The feedback loop control device comprises a transimpedance amplifier, a DC de-coupler, a frequency to voltage converter, a controller, and a voltage-controlled high-voltage power supply that provides a tip to counter-electrode voltage to the capillary tip and counter-electrode interface. The feedback loop control device measures the modulation frequency of ionization currents and provides a feedback adjustment of the tip-to-counter-electrode voltage to maintain ionization efficiency.

REFERENCES:
patent: 6952013 (2005-10-01), Granger et al.
patent: WO 02/095362 (2002-11-01), None
Bruins A.P. , “Mechanistic aspects of electrospray ionization,” Journal of Chromatography A, vol. 794, pp. 345-347, 1998.
Cech et al., “Practical implications of some recent studies in electrospray ionization fundamentals,” Mass Spectrometry Reviews, vol. 20, pp. 362-387, Nov. 16, 2001.
Taylor G. I., “Disintegration of water drops in an electric field,”Proceedings of the Royal Society of London, vol. A280, pp. 383-397, Feb. 21, 1964.
R. Juraschek and F. W. Röllgen, “Pulsation phenomena during electrospray ionization,” International Journal of Mass Spectrometry, 177:1-15, Apr. 6, 1998.
Lee, et al., “Taylor cone stability and ESI performance for LC-MS at low flow rates,” Proceedings of the American Society of Mass Spectrometry, Jun. 2-6, 2002.

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