Ion-sensitive fluorescence optical sensor

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

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C422S082070, C422S082080

Reexamination Certificate

active

07029630

ABSTRACT:
The present invention relates to optical ion sensors, including fluorescence optical ion sensors for use in liquid media in the fields of biology, biotechnology, chemistry, medicine, etc. The present invention provides for optical ion sensors that may be attached to dry hydrophilic or hydrophobic surfaces so as to allow continuous sensing. The optical sensors of the present invention may be sterilized and stored for extended periods of time before use.

REFERENCES:
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Garoff, H. and Ansorge, W., “Improvements of DNA Sequencing Gels,”Anal. Biochem. 115:450-457, Academic Press, Inc. (1981).
Sheu, M.-S., et al., “Biomaterials Surface Modification Using Plasma Gas Discharge Processes,” inEncyclopedic Handbook of Biomaterials and Bioengineering, Part A. Materials, 865-894, Wise, D.L., et al., eds., Marcel Dekker, New York (1995).
Tolosa, L., et al., “Noninvasive Measurement of Dissolved Oxygen in Shake Flasks,”Biotechnology and Bioengineering 80:594-597, Wiley Periodicals, Inc. (2002).
Co-Pending U.S. Non-provisional Patent Application No. 10/609,720, filed Jun. 30, 2003.

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