Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1987-08-24
1992-08-04
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
540469, 540472, 549200, 549348, 549349, 549350, 549351, 549352, 436 74, C07D41902, C07D32100, G01N 3320
Patent
active
051360330
ABSTRACT:
Novel fluorogenic ionophores have been synthesized which selectively bind ions such as potassium and sodium, even in neutral aqueous and alcoholic media and respond to such binding by fluorescence quenching or enhancement. These ionophores are ideal for the selective and direct determination of ions in biological or environmental samples and the like. The ionophores are also suitable for incorporation into fiber optic-based sensors for the continuous in vivo or in vitro monitoring of metal ions in blood or other biological fluids.
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Takagi et al "Crown Compounds . . . " Topic Curr. Chem. 121 39-65 (1984).
Merck index p. 1247.
K. W. Street, Jr., et al. "A New Metal Sensitive Fluorescence Reagent" Analytical Ltrs, 19(7 and 8), 735-745 (1986).
A. P. de Silva "Fluorescent Signalling Crown Ethers; `Switching On` of . . . " J. Chem. Soc. Chem. Commun. 1986, pp. 1709-1710.
S. Fujine et al. "Lithium Isotope Separation by Displacement Chromo . . . " Jrnl of Nuclear Science and Techn. 20(5), pp. 439-440 (May 1983).
J. P. Konopelski et al. "Synthesis, Cation Binding, and Photophysical Prop . . . " J. Chem. Soc. Chem. Commun., 1985, pp. 433-435.
Hammond George S.
Lucas Mariann E.
Masilamani Divakaran
Allied-Signal Inc.
Chang Celia
Fuchs G. H.
Ivy C. Warren
Stewart II R. C.
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