Ion mobility based separation methods and apparatus

Details Ion mobility based separation methods and apparatus Ion mobility based separation methods and apparatus

2009-10-31

2011-11-22

Wells, Nikita (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S281000, C250S282000, C250S287000

Reexamination Certificate

active

08063361

ABSTRACT:
The present invention describes separating components in a sample in an ion mobility based spectrometer using at least one matching property of the components other than the molecular properties in conventional ion mobility measurements in noble drift gases to enhance separation and resolution of the sample. Separation based on the matching property is realized by altering the drift media of the IMS. Besides altering drift media, energy level of ions and/or drift media are also controlled during the separation process. This invention describes an ion mobility apparatus wherein an energy source is added to the IMS that provides additional energy to the ions and/or drift media and tuning methods that involve selecting drift media and optimizing the energy level in order to achieve optimal performance.

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