Ion exchange cryptands covalently bound to substrates

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C540S145000, C549S010000, C549S347000, C549S348000

Reexamination Certificate

active

06867295

ABSTRACT:
One embodiment of the invention comprises an ion exchange composition formed by reacting unsaturated carbon to carbon moieties pendant from derivatized ion binding cryptands with a support substrate under free radical activation conditions to form a covalent bond therebetween.In another embodiment, a cryptand ion exchange composition is made by covalently bonding unsaturated carbon to carbon moieties pendant from a derivatized ion binding cryptands with unsaturated carbon to carbon moieties pendant from a support substrate under free radical activation conditions to form covalent bond.

REFERENCES:
patent: 4224415 (1980-09-01), Meitzner et al.
patent: 4880923 (1989-11-01), Brois et al.
patent: 4943375 (1990-07-01), Bradshaw et al.
patent: 5393892 (1995-02-01), Krakowiak et al.
patent: 5792331 (1998-08-01), Srinivasan et al.
patent: 5865994 (1999-02-01), Riviello et al.
patent: 5968363 (1999-10-01), Riviello et al.
patent: 6074541 (2000-06-01), Srinivasan et al.
patent: 6200478 (2001-03-01), Chorush et al.
patent: 6262257 (2001-07-01), Gale et al.
patent: 20020177680 (2002-11-01), Hubbell et al.
patent: 1 081 163 (2001-03-01), None
patent: 55-018434 (1980-02-01), None
patent: 59-145022 (1984-08-01), None
patent: 61-033220 (1986-02-01), None
patent: 04-346064 (1992-12-01), None
patent: 11-043514 (1999-02-01), None
patent: 11-240864 (1999-09-01), None
patent: 2000-356702 (2000-12-01), None
patent: WO 9928355 (1999-06-01), None
patent: WO 0043539 (2000-07-01), None
Babb, D.A., et al., “Synthesis of Hydroxymethyl-Functionalized-Diazacrowns and Cryptands,”Journal of Heterocyclic Chemistry23:609-613 (1986).
Blasius, E., et al., “Preparation and Application of Polymers with Cyclic Polyether Anchor Groups,”Pure&App. Chem.54(11):2115-2128 (1982).
Bradshaw, J.S., et al., “Stable Silica Gel-Bound Crown Ethers. Selective Separation of Metal Ions and a Potential for Separations of Amine Enantionmers,”Journal of Inclusion Phenomena and Molecular Recognition in Chemistry7:127-136 (1989).
Bradshaw, J.S., et al., “Silical gen-bound aza-crowns for the selective removal and concentration of metal ions,”Pure&Appl. Chem.61:1619-1624 (1989).
Bradshaw, JS., et al., “Aza-Crown Macrocycles,”The Chemistry of Heterocyclic Compounds, vol. 51, ed. Taylor, E.C., Wiley, New York, 1993, p. 246.
Griesbaum, K, “Problems and Possibilities of the Free-Radical Addition of Thiols to Unsaturated Compounds,”Angew. Chem. Internat. Edit.vol. 9, No. 4, 273-287 (1970).
Haoyun, A., et al., “Macropolycyclic Polyethers (Cages) and Related Compounds,”Chemical Reviews92:543-572 (1992).
Haoyun, A., et al., “Synthesis and Complexation Properties of Suitcase-Shaped Macrotricyclic and Butterfly-Shaped Macrobicyclic Polyether Ligands,”Journal of Organic Chemistry57:4998-5005 (1992).
Krakowiak, K.E., et al., “Syntheses of the Cryptands. A Short Review,”Israel Journal of Chemistry32:3-13 (1992).
Krakowiak, K.E., et al., “One-step Methods to Prepare Cryptands and Crowns Containing Reactive Functional Groups,”,Journal of Heterocyclic Chemistry27:1011-1014 (1990).
Krespan, C.G., “Functionalized Macroheterobicyclic Compounds,”Journal of Organic Chemistry45:1177-1180 (1980).
Lamb and Smith, “Review: Application of Macrocyclic Ligands to Ion Chromatography,”J. Chromatogr.546:73-88 (1991).
Lamb, et al. (Editors), “Variable Capacity Columns for Gradient Elution Anion Chromatography Based on Macrocyclic Complexes,”Advances in Ion Chromatography, vol. 2, Century International, Franklin, MA, pp 215-231 (1990).
Lamb, J.D., et al., “Chemically suppressed anion chromatography based on macrocycle-cation complexation,”J. Chromatogr., 482:367-380 (1989).
Lamb, J.D., et al., “Anion chromatography with a crown ether-based stationary phase and an organic modifier in the eluent,”J. Chromatogr., 640:33-40 (1993).
Lamb, J.D., et al., “A comparison of gradient capacity anion chromatography using macrocycles D-2.2.2 and D-2.2.1 in contrast or variable temperature mode,”Talanta, 39(8):923-930 (1992).
Montanari, F., et al., “Phase-transfer Catalytic Activity of Polymer-supported Macrocyclic Polyethers,”British Polymer Journal, 16:212-218 (1984).
Montanari, F., et al., “Hydroxymethyl Derivatives of 18-Crown-6 and [2.2.2]Cryptand: Versatile Intermediates for the Synthesis of Lipophilic and Polymer-Bonded Macrocyclic Ligands,”,J. Org. Chem., 47:1298-1302 (1982).
Montanari, F., et al., Hydroxymethyl 18-Crown-6 and Hydroxymethyl [2.2.2]Cryptand: Versatile Derivatives for Binding the Two Polyethers to Lipophilic Chains and to Polymer Matrices,Tetrahedron Letters, No. 52, 5055-5058 (1979).
Niederhauser, T.L., et al., “High-performance anion-exchange chromatographic separations of carbohydrate on a macrocycle-based stationary phase with eluents or relatively low pH and concentation,”Journal of Chromatography A, 804:69-77 (1998).
Smith, R.G., et al., “Use of step gradients of different polymeric substrates in the separation of anions by macrocycle-based ion chromatography,”Journal of Chromatography A, 671:89-94 (1994).
Dietrich, B., “Cryptands,” inComprehensive Supramolecular Chemistry, Atwood et al. eds., Jean-Marie Lehn—Chairman of the Editorial Board, New York: Pergamon, 1996, vol. 1, G.W. Gokel, ed., pp. 154-157, 186, 192.
Nakajima M et al., “Liquid Chromatography of Alkali and Alkaline Earth Metal Salts on Poly(Benzo-15-Crown-5)-and Bis(Benzo- 15-Crown-5)-Modified Silicas,”Analytical Chemistry, American Chemical Society. Columbus, OH 55(3):463-467 (1983).
Watanabe, H. et al., “Synthesis and phase-transfer catalytic activity of novel chiral crown ethers immobilized onto polystyrene supports,”Reactive&Functional Polymers, Elsevier Science Publishers BV, NL 37(1-3):101-109 Jun. 1998.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Ion exchange cryptands covalently bound to substrates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ion exchange cryptands covalently bound to substrates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ion exchange cryptands covalently bound to substrates will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3398687

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.