Radiant energy – Ionic separation or analysis – Methods
Reexamination Certificate
2007-04-13
2010-12-28
Wells, Nikita (Department: 2881)
Radiant energy
Ionic separation or analysis
Methods
C250S281000, C250S283000, C250S290000, C250S3960ML, C250S42300F, C250S424000
Reexamination Certificate
active
07858929
ABSTRACT:
A method for reducing the energy spread of ions over a specific and limited mass to charge ratio range is disclosed, along with an ion deceleration arrangement for implementing such a method. An electric field, having an electric field strength E is generated by a deceleration electrode arrangement (250). Ions of a specific and limited mass to charge ratio range, but having a spread of energies, are directed into the decelerating electric field generated by the deceleration electrode arrangement (250). The decelerating electric field is then removed, once substantially all of the ions of the specific mass to charge ratio range have entered the decelerating electric field. By matching the electric field strength E to the energy spread of the ions upon entry into the electric field, the energy spread of the said ions is reduced. Preferred embodiments of the invention employ energy dispersion upstream of the ion deceleration arrangement. For example, an ion mirror arrangement (200) may be used, the ions reflecting off an ion mirror (220) within that ion mirror arrangement (200) to promote energy defocusing.
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V. Frankevich et al., “Deceleration of High-Energy Matrix-Assisted Laser Desorption/Ionization Ions in an Open Cell for Fourier Transform Ion Cyclotron Resonance Mass Spectrometry,” Rapid Communications in Mass Spectrometry, Heyden (London), vol. 15, (2001), pp. 2035-2040.
Grinfield Dimitry E.
Makarov Alexander
Monastyrskiy Mikhail
Katz Charles B.
Thermo Fisher Scientific (Bremen) GmbH
Wells Nikita
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