Ion channel receptor and uses thereof

Details Ion channel receptor and uses thereof Ion channel receptor and uses thereof

2006-10-17

2006-10-17

O'Hara, Eileeen B. (Department: 1647)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023500, C530S350000

Reexamination Certificate

active

07122648

ABSTRACT:
The present invention provides for nucleic acid sequences that encode novel mammalian intracellular signaling polypeptides, designated MINC102. The invention also provides assay systems that may be used to detect and/or measure agents that bind the MINC102 gene product. The present invention also provides for diagnostic and therapeutic methods for treating muscle atrophy by inhibiting expression or activity of MINC102.

REFERENCES:
Bodine, et al, (2001) Science 294: 1704-1708.
Bodine, et al. 2001 Nature Cell Biology 3:1014-1019.
Rommel, et al (1999) Science 286: 1738-1741.
Coleman, et al. (1995) The Journal of Biological Chemistry 270: 12109-12116.
Rommel, et al. Nature (2001) 3: 1009-1013.

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