Iodine containing organic carbonates for use as radiographic age

Details Iodine containing organic carbonates for use as radiographic age Iodine containing organic carbonates for use as radiographic age

1976-04-22

1977-05-10

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424 5, C07C 6996

Patent

active

040228142

ABSTRACT:
Iodo-aryl carbonates, such as for example, p-iodo-benzyl carbonates, p-iodo-sec-phenethyl carbonates, p-iodo-phenethyl carbonates, p-iodo-phenyl carbonates, 3-(p-iodophenyl)propyl carbonates, 3-(p-iodophenyl)butyl carbonates, 2-(p-iodobenzyl)butyl carbonates and 2-(p-iodobenzyl)-n-hexyl carbonates, for use as radiographic media in connection with such techniques as x-ray applications including myelography, salpingography, lymphography and bronchography. An effective quantity of iodinated organic carbonate provides x-ray contrast, and the compounds of the invention may be characterized generally as carbonates having the general formula ##STR1## wherein R represents an alkyl group having from 4 to 10 carbon atoms and R' represents an iodinated phenyl linked to the ester oxygen through an alkyl chain consisting of 1 to 3 carbon atoms.

REFERENCES:
patent: 3676486 (1972-07-01), Nikles
J. Chem. Soc. (B), 1971, pp. 622-627.

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