Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1983-07-06
1984-09-04
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
424 11, 2601125R, A61K 3700, A61K 4300, G01N 3300, C07C10352
Patent
active
044696809
ABSTRACT:
A series of vasopressin antagonists which have a 3'-iodo-tyrosine unit at position 2 are prepared by iodination of the tyrosine congeners. The compounds have antagonist activity manifested by an aquaretic effect and, also, are useful in studying various biological reactions.
REFERENCES:
patent: 4367225 (1983-01-01), Manning et al.
G. Flouret et al., Biochemistry 16 2119 (1977).
Huffman William F.
Moore Michael L.
Edgerton William H.
Foggio Richard D.
Lourie Alan D.
Phillips Delbert R.
SmithKline Beckman Corporation
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