Iodinated clonidine derivatives as radioactive imaging tracers

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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548315, A61K 4300, C07D40330

Patent

active

048836494

ABSTRACT:
Iodinated clonidine derivatives useful, inter alia, as a probe for identification and characterization of .alpha..sub.2 -adrenergic receptor sites and as tracers for imaging techniques such as positron emission tomography or computer assisted tomography. Binding competition studies have indicated that p-iodoclonidine, for example, is a particularly efficacious binder for .alpha..sub.2 -adrenergic sites.

REFERENCES:
patent: 4262005 (1981-04-01), McCarthy et al.

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