Investigating body function

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...

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250303, 2603972, 424 1, 424 9, A61K 2900, A61K 4300

Patent

active

042028760

ABSTRACT:
Body function of a mammal is investigated using a .gamma.-emitting .sup.75 Se or .sup.123m Te labelled derivative of a bile acid or bile salt. Thus bowel function may be investigated by oral administration of the labelled compound followed, after a suitable period of time, by either a whole body count or a faecal count of radioactivity. Preferred bile acids and salts are substituted either at the 19-position or in the C-17 side chain.

REFERENCES:
patent: 3784576 (1974-01-01), Counsell
patent: 3993741 (1976-11-01), Otto
patent: 4024234 (1977-05-01), Monks et al.
patent: 4041145 (1977-08-01), Van der Veek
patent: 4083947 (1978-04-01), Monks et al.

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