Invertebrate apoptosis gene `GRIM` and methods of producing the

Details Invertebrate apoptosis gene `GRIM` and methods of producing the Invertebrate apoptosis gene `GRIM` and methods of producing the

1996-07-22

1998-12-08

Kemmerer, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 4351723, 4352523, 435325, 435348, 536 231, 536 243, 536 2433, 536 241, 536 235, C07K 14435, C12N 121, C12N 510, C12N 1512

Patent

active

058467688

ABSTRACT:
Disclosed is a Drosophila grim gene and encoded GRIM polypeptide, an activator of apoptosis. The disclosed nucleic acid sequences are useful in the production of the protein and as hybridization probes and primers. Expression of the GRIM protein causes programmed cell death. Preferred embodiments include expression of grim under the control of an inducible promoter and the use of such a construct in the control of an insect population.

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