Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Patent
1995-06-07
1998-06-16
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
530338, 530339, 530344, 588361, A61K 3800, C07B 3712
Patent
active
057672385
ABSTRACT:
This invention relates to a method of inverse solid phase synthesis in which reactants are reacted in solution and a solid phase matrix is used to separate unreacted reactants from desired product.
REFERENCES:
patent: 5288514 (1994-02-01), Ellman
WPIDS abstract 90-287857 (JP 02204474) 1990.
Bayer and Mutter, Nature, 237:512-513 (1972).
Bayer, et al., J. Am. Chem. Soc., 96:7333-7336 (1974).
Bonora, et al., Nucleic Acids Res., 18:3155-3159 (1990).
Bayer, et al., Peptides: Chemistry, Structure, Biology, 425-432.
Product Information for the Empore.TM. Disk.
Fodor et al., Science, 251:767-773 (1991).
Geysen, et al., Proc. Natl. Acad. Sci. U.S.A., 81:3998-4001 (1987).
Frank and Doring, Tetrahedron 4:6031-6040 (1988).
Eritja, et al. Tetrahedron 47:4113-4120 (1991).
Maeji et al., J. Immun. Methods 146:83-90 (1992).
Haralambidis et al., Nucleosides and Nucleotides 10:333-337 (1991).
Juby, et al., Tetrahedron Letters, 32:879-882 (1991).
Houghton, et al., Nature, 354:84-86 (1991).
Cwirla, et al., Proc. Natl. Acad. Sci. U.S.A., 87:6378-6382 (1990).
Leznoff, Accounts of Chemical Research, 11:327-333 (1978).
Xu, et al., Can. J. Chem., 61:1405-1409 (1982).
Pittman and Smith, J. Am. Chem. Soc., 97:1749 (1975).
Wang and Fox, J. Org. Chem., 59:5358-5364 (1994).
Angeletti, et al., Tetrahedron Letters, 29:2261-2264 (1988).
Borin Michael
CombiChem, Inc.
Tsang Cecilia J.
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