Intravenously injectable immune serum globulin

Details Intravenously injectable immune serum globulin Intravenously injectable immune serum globulin

1981-08-24

1983-08-02

Bleutge, John C.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

424 85, 424101, 260112B, C08L 8900

Patent

active

043966080

ABSTRACT:
A composition is disclosed which comprises a solution in a pharmaceutically acceptable carrier of an immune serum globulin, said solution having an ionic strength and a pH to maintain the monomer content and the actual and latent anticomplement activity of the immune serum globulin such that the composition is intravenously injectable. Novel methods are disclosed for preparing the above composition.

REFERENCES:
patent: 4093606 (1978-06-01), Coval
patent: 4186192 (1980-01-01), Lundblad

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