Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1991-08-09
1993-10-05
Rosenbaum, C. Fred
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604 56, 604 82, 6048921, A61M 3700
Patent
active
052500284
ABSTRACT:
A drug formulation chamber for an intravenous administration set is provided. The intravenous administration set includes a container of an IV fluid, a drip chamber, a drug formulation chamber, and an adapter-needle assembly. The drug formulation chamber has a fluid inlet and a fluid outlet for maintaining a flow of IV fluid through the chamber. A portion of the chamber wall is comprised of a material which is permeable to the drug but which prevents convective loss of the IV fluid. A transdermal-type drug delivery device is adhered to the semipermeable/microporous wall portion. Drug is delivered by the delivery device through the wall portion using permeation enhancers and into the flowing IV fluid. The device delivers drug into the IV fluid at a rate that is independent of the flow rate of IV fluid through the formulation chamber. The rate of drug delivery from the device into the IV fluid is controlled by either the wall portion or a membrane layer in the drug delivery device. A plurality of drug delivery devices may be adhered to the wall portion to deliver a plurality of drugs or to deliver a single drug at a higher dosage rate.
REFERENCES:
patent: 3536809 (1970-10-01), Applezweig
patent: 3598122 (1971-08-01), Zaffaroni
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3699963 (1972-10-01), Zaffaroni
patent: 3726276 (1973-04-01), Schumann et al.
patent: 3731683 (1973-05-01), Zaffaroni
patent: 3734097 (1973-05-01), Zaffaroni
patent: 3742951 (1973-07-01), Zaffaroni
patent: 3787571 (1974-01-01), Higuchi
patent: 3788316 (1974-01-01), Mora
patent: 3964482 (1976-06-01), Gerstel et al.
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4031894 (1977-06-01), Urquhart et al.
patent: 4060084 (1977-11-01), Chandrasekaran et al.
patent: 4144317 (1979-03-01), Higuchi et al.
patent: 4479793 (1984-10-01), Urquhart et al.
patent: 4511353 (1985-04-01), Theeuwes
patent: 4533348 (1985-08-01), Wolfe et al.
patent: 4552555 (1985-11-01), Theeuwes
patent: 4606734 (1986-08-01), Larkin et al.
patent: 4664650 (1987-05-01), Urquhart et al.
patent: 4669458 (1987-06-01), Abraham et al.
patent: 4740103 (1988-04-01), Theeuwes
patent: 4740200 (1988-04-01), Theeuwes
patent: 4740201 (1988-04-01), Theeuwes
patent: 4792450 (1988-12-01), Kydonieus et al.
patent: 4837027 (1989-06-01), Lee et al.
patent: 4871352 (1989-10-01), Tron
patent: 5160320 (1992-11-01), Yum et al.
J. Pharma Sci., vol. 52, pp. 1145-1149, (1963).
J. Pharma Sci., vol. 53, pp. 798-802, (1964).
J. Pharma Sci., vol. 54, pp. 1459-1464, (1965).
J. Pharma Sci., vol. 55, pp. 840-843 and pp. 1224-1229 (1966).
Encyl. Polymer Sci. Technol., vol. 5, pp. 65-82 and vol. 9, pp. 794-807 (1986).
PCT Search Report, PCT/US90/00871 (This Appl.) (Jun. 6, 1990) Citations included in this IDC.
PCT, International Preliminary Examination Report, PCT/US90/00871 (This Appl.) (May 23, 1991).
Theeuwes Felix
Yum Su I.
ALZA Corporation
Bockelman Mark
Mandell Edward L.
Meece R. Scott
Miller D. Byron
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