Intravenous system for delivering a beneficial agent

Details Intravenous system for delivering a beneficial agent Intravenous system for delivering a beneficial agent

1990-08-15

1991-09-03

Pellegrino, Stephen C.

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604 80, 6048901, 604 83, A61M 3700

Patent

active

050450590

ABSTRACT:
A drug formulation chamber for an intravenous administration set is provided. The intravenous administration set includes a container of an IV fluid, a drip chamber, a drug formulation chamber, and an adapter-needle assembly. The drug formulation chamber has a fluid inlet and a fluid outlet for maintaining a flow of IV fluid through the chamber. A portion of the chamber wall is comprised of a window material which allows the drug to diffuse therethrough but which prevents convective loss of the IV fluid. A flow distributor is provided within the chamber for distributing the flow of IV fluid along the interior surface of the window. A transdermal-type drug delivery device is adhered to the exterior surface of the window. Drug is delivered by the delivery device through the window and into the flowing IV fluid. The device delivers drug into the IV fluid at a rate that is independent of the flow rate of IV fluid through the formulation chamber. The rate of drug delivery from the device into the IV fluid is controlled by either the window itself or by a membrane layer in the drug delivery device. A plurality of drug delivery devices may be adhered to the window to deliver a plurality of drugs or to deliver a single drug at a higher dosage rate. A similar window may be placed in an IV bag to deliver a drug into the IV fluid therein.

REFERENCES:
patent: 3536809 (1970-10-01), Applezweig
patent: 3598122 (1971-08-01), Zaffaroni
patent: 3598123 (1971-10-01), Zaffaroni
patent: 3699963 (1972-10-01), Zaffaroni
patent: 3731683 (1973-05-01), Zaffaroni
patent: 3734097 (1973-05-01), Zaffaroni
patent: 3742951 (1973-07-01), Zaffaroni
patent: 3787571 (1974-01-01), Higuchi
patent: 3797494 (1974-03-01), Zaffaroni
patent: 3964482 (1976-06-01), Gerstel et al.
patent: 3996934 (1976-12-01), Zaffaroni
patent: 4031894 (1977-06-01), Urquhart et al.
patent: 4060084 (1977-11-01), Chandrasekaran et al.
patent: 4144317 (1979-03-01), Higuchi et al.
patent: 4439183 (1984-03-01), Theeuwes
patent: 4511353 (1985-04-01), Theuwes
patent: 4533348 (1985-08-01), Wolfe et al.
patent: 4534757 (1985-08-01), Geller
patent: 4740103 (1988-04-01), Theeuwes
patent: 4740197 (1988-04-01), Theeuwes
patent: 4740200 (1988-04-01), Theeuwes
patent: 4740201 (1988-04-01), Theeuwes
patent: 4741734 (1988-05-01), Theeuwes
patent: 4857052 (1989-08-01), Theeuwes
patent: 4871352 (1989-10-01), Tran
J. Pharma Sci. vol. 52, pp. 1145-1149 (1963).
J. Pharma Sci. vol. 53, pp. 798-802, (1964).
J. Pharma Sci. vol. 54, pp. 1459-1464 (1985).
J. Pharma Sci. vol., 55, pp. 840-843, and 1224-1239 (1966).
Encyl. Polymer Sci. Techol., vols. 5 and 9, pp. 65-82 and pp. 794-807, (1986).

Affiliated with

Also associated with

Rating

Intravenous system for delivering a beneficial agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intravenous system for delivering a beneficial agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intravenous system for delivering a beneficial agent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1006225