Intravascular stent and method

Details Intravascular stent and method Intravascular stent and method

1995-06-07

1997-10-21

Dudash, Diana

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

427 224, 427352, B05D 300, B05D 138, A61J 300, A61L 2700

Patent

active

056794002

ABSTRACT:
A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.

REFERENCES:
patent: 4292965 (1981-10-01), Nash et al.
patent: 4529614 (1985-07-01), Burns
patent: 4532929 (1985-08-01), Mattei et al.
patent: 4548736 (1985-10-01), Muller et al.
patent: 4733665 (1988-03-01), Palmaz
patent: 4753652 (1988-06-01), Langer et al.
patent: 4800882 (1989-01-01), Gianturco
patent: 4869909 (1989-09-01), Takahashi et al.
patent: 4886062 (1989-12-01), Wiktor
patent: 4888009 (1989-12-01), Lederman et al.
patent: 4894231 (1990-01-01), Moreau et al.
patent: 4955899 (1990-09-01), Della Corna et al.
patent: 5019090 (1991-05-01), Pinchuk
patent: 5102417 (1992-04-01), Palmaz
patent: 5176907 (1993-01-01), Leong
patent: 5192308 (1993-03-01), Ostapchenko
patent: 5221698 (1993-06-01), Amiden et al.
patent: 5234456 (1993-08-01), Silverstrini
patent: 5242391 (1993-09-01), Place et al.
patent: 5290266 (1994-03-01), Rohling et al.
patent: 5295978 (1994-03-01), Fan et al.
patent: 5380299 (1995-01-01), Fearnot et al.
patent: 5416131 (1995-05-01), Wolff et al.
patent: 5443496 (1995-08-01), Schwartz et al.
patent: 5447724 (1995-09-01), Helmus et al.
patent: 5510077 (1996-04-01), Dinh et al.
patent: 5558900 (1996-09-01), Fan et al.
"Seeding of Intravascular Stents with Genetically Engineered Endothelial Cells" by Dicket et al, in Circulation, vol. 80, No. 5 Nov. 1989.
"Restenosis and the Proportinal Neointimal Response to Coronary Artery Injury: Results in a Porcine Model" by Schwartz et al., in JACC, vol. 19, No. 2, Feb. 1992 pp. 267-274.
"Restenosis After Baloon Angioplasty" by Schwartz, et al., in Circulation, vol. 82, No. 6, Dec. 1990.

Affiliated with

Also associated with

Rating

Intravascular stent and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intravascular stent and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intravascular stent and method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1004877