Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure
Patent
1995-04-27
1998-11-17
Yu, Mickey
Prosthesis (i.e., artificial body members), parts thereof, or ai
Arterial prosthesis
Stent structure
623 11, 623 12, 606194, 606195, 600 36, A61F 206
Patent
active
058370080
ABSTRACT:
A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.
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Berg Eric P.
Dror Michael
Tuch Ronald J.
Wolff Rodney G.
Cuddihy Francis K.
Latham Daniel W.
Medtronic Inc.
Patton Harold R.
Yu Mickey
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