Coating processes – Medical or dental purpose product; parts; subcombinations;... – Fluid barrier or fluid transporting product – other than...
Patent
1993-04-26
1995-11-07
Dudash, Diana
Coating processes
Medical or dental purpose product; parts; subcombinations;...
Fluid barrier or fluid transporting product, other than...
427 225, 427 228, B05D 102, B05D 118, B05D 138
Patent
active
054646502
ABSTRACT:
A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent during expansion of the stent and also controls the administration of drug following implantation. The adhesion of the coating and the rate at which the drug is delivered can be controlled by the selection of an appropriate bioabsorbable or biostable polymer and the ratio of drug to polymer in the solution. By this method, drugs such as dexamethasone can be applied to a stent, retained on a stent during expansion of the stent and elute at a controlled rate.
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Berg Eric P.
Dror Michael
Tuch Ronald J.
Wolff Rodney G.
Dudash Diana
Latham Daniel W.
Medtronic Inc.
Patton Harold R.
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