Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-03-21
2006-03-21
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S069100, C514S04400A, C536S023100
Reexamination Certificate
active
07015040
ABSTRACT:
Disclosed is a process for providing for expression of an exogenous nucleic acid in an extravascular parenchymal cell of a mammal. The nucleic acid is inserted into a vessel of a mammal and the permeability of the vessel is increased. Increasing permeability of the vessel allows delivery of the nucleic acid to an extravascular parenchymal cell.
REFERENCES:
patent: 6379966 (2002-04-01), Monahan et al.
patent: 6897068 (2005-05-01), Monahan et al.
Budker Vladimir G.
Hagstrom James E.
Hegge Julia
Herweijer Hans
Wolff Jon A.
Ekena Kirk
Johnson Mark K.
Ketter James
Mirus Bio Corporation
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