Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-12-12
2006-12-12
Woitach, Joseph (Department: 1632)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S023100, C536S024500
Reexamination Certificate
active
07148205
ABSTRACT:
Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian vessel such as a tail vein or artery. Prior to insertion, subsequent to insertion, or concurrent with insertion the permeability of the vessel is increased thereby the genetic material is delivered to the parenchymal cell altering endogenous properties of the cell.
REFERENCES:
patent: 6627616 (2003-09-01), Monahan et al.
Budker Vladimir G.
Hagstrom James E.
Monahan Sean D.
Rozema David B.
Slattum Paul M.
Ekena Kirk
Johnson Mark K.
Mirus Bio Corporation
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