Intravascular delivery of methylprednisolone

Details Intravascular delivery of methylprednisolone Intravascular delivery of methylprednisolone

2006-03-28

2006-03-28

McDermott, Corrine (Department: 3738)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Drug delivery

C623S001450

Reexamination Certificate

active

07018405

ABSTRACT:
The present invention provides improved devices and methods for minimizing and/or inhibiting restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides luminal prostheses which allow for programmed and controlled methylprednisolone delivery with increased efficacy to selected locations within a patient's vasculature to inhibit restenosis. An intraluminal delivery prosthesis may comprise an expansible structure and means on or within the structure for releasing methylprednisolone into the body lumen to inhibit smooth muscle cell proliferation.

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