Radiant energy – Invisible radiant energy responsive electric signalling – With or including a luminophor
Patent
1990-06-18
1991-04-16
Berman, Jack I.
Radiant energy
Invisible radiant energy responsive electric signalling
With or including a luminophor
250367, G01T 1161, G01T 120, G01T 1203
Patent
active
050085468
ABSTRACT:
An intraoperative radiation probe is devised to detect radiolabelled malignant tissues by being selectively sensitive to beta radiation while insensitive to gamma radiation. The probe is comprised of two plastic scintillators optically coupled to corresponding photomultiplier tubes via corresponding light pipes. One of the plastic scintillators is shielded against beta radiation while the other is left to detect both beta and gamma radiation. The gamma radiation sensitivity of the dual probes is empirically established and used as a weighted factor to subtract the outputs of the two probes to leave a signal indicative of the beta radiation emitted by the radiolabelled tissue. Because of the shorter range of beta radiation within tissue, only near radiolabelled tissue is detected by the probe while strongly radiolabelled, more distant tissues exposing the probe to gamma radiation are ignored. The reliably identified near radiolabelled tissues can then be surgically removed. The probe is usable in any application where local beta radiation is to be differentiated from other types and sources of radiation.
REFERENCES:
patent: 4267446 (1981-05-01), Brown et al.
Hickernell, T. et al., "Dual-Detector Probe for Surgical Tumor Staging", J. Nucl. Med. vol. 29, No. 6, Jun. 1988.
Daghighian Farhad
Hoffman Edward J.
Mazziotta John C.
Berman Jack I.
Hanig Richard
The Regents of the University of California
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