Intraocular perfluorcarbon compositions and surgical methods of

Details Intraocular perfluorcarbon compositions and surgical methods of Intraocular perfluorcarbon compositions and surgical methods of

1997-07-30

1999-07-27

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

A61F 214

Patent

active

059286636

ABSTRACT:
Mixtures of perfluorocarbon liquids having an index of refraction different than water enable their visualization for use in intraocular surgery. These mixtures are used in the surgical repair retinal tears or detachments. Mixtures of perfluoroperhydrophenanthrene and perflurooctane or perfluorooctyl bromide are preferably used.

REFERENCES:
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Chang, S., et al., Experimental studies of tolerance to intravitreal perfluoro-N-octane liquid, Retina, 11/4:367-374, 1991.
Conway, J.D., et al., Perfluorooctylbromide (PFOB) as a vitreous substitute in non-human primates, Internat Ophth, 17:259-264, 1993.
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Refojo, M.F., et al., The refractive index of Vitreon, Ophth Surg, (letter to the editor), 23/6:436, Jun. 1992.
Schulman, J.A., et al., Management of giant retinal tears with perfluoroperhydrophenanthrene (Vitreon) Jpn J Ophthalmol, 37:70-77, 1993.
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