Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-06-23
1996-06-04
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514912, 514255, A61K 31415
Patent
active
055233163
ABSTRACT:
Improved ophthalmic irrigating solutions are described. The solutions include one or more drugs for controlling intraocular pressure, an antioxidant/free radical scavenger, electrolytes, a cellular energy source, bicarbonate, and a buffer. Methods of using the solutions in connection with ophthalmic surgical procedures are also described.
REFERENCES:
patent: 3468887 (1969-09-01), Stahle et al.
patent: 4461904 (1984-07-01), York, Jr.
patent: 4515800 (1985-05-01), Cavero et al.
patent: 4517199 (1985-05-01), York, Jr.
patent: 4550022 (1985-10-01), Garabedian et al.
patent: 4587257 (1986-05-01), DeSantis
patent: 4975419 (1990-12-01), Newton et al.
patent: 5212196 (1993-05-01), House et al.
patent: 5215991 (1993-06-01), Burke
Evans, Dale B., et al., ".beta.-Adrenergic Receptor Blockers as Therapeutic Agents", Annual Reports in Medicinal Chemistry, vol. 14, pp. 81-90 1979.
Machin, Peter J., et al., ".beta..sub.1 -Selective Adrenoceptor Antagonists. 2. 4-Ether-Linked Phenoxypropanolamines", Journal of Medicinal Chemistry, vol. 26, No. 11, pp. 1570-1576 (Nov. 1983).
Machin, Peter J., et al., ".beta..sub.1 -Selective Adrenoceptor Antagonists. 3. 4-Azolyl-Linked Phenoxypropanolamines", Journal of Medicinal Chemistry, vol. 27, No. 4, pp. 503-509 (Apr. 1984).
Pitha, Josef, et al., ".beta.-Adrenergic Antagonists with Multiple Pharmacophores: Persistent Blockade of Receptors", Journal of Medicinal Chemistry, vol. 26, No. 1, pp. 7-11 (Jan. 1983).
Kierstead, R. W., et al., ".beta..sub.1 -Selective Adrenoceptor Antagonists. 1. Synthesis and .beta.-Adrenergic Blocking Activity of a Series of Binary (Aryloxy) propanolamines", Journal of Medicinal Chemistry, vol. 26, No. 11, pp. 1561-1567 (Nov. 1983).
Erhardt, Paul W., et al., "Ultra-Short-Acting .beta.-Adrenergic Receptor Blocking Agents. 3. Ethylenediamine Derivatives of (Aryloxy) propanolamines Having Esters on the Aryl Function", Journal of Medicinal Chemistry, vol. 26, No. 8, pp. 1109-1112 (Aug. 1983).
Baldwin, John J., et al., ".beta..sub.1 -Selective Adrenoceptor Antagonists: Examples of the 2-[4-[3-(Substituted-amino)-2-hydroxypropoxy[phenyl[imidazole Class", Journal of Medicinal Chemistry, vol. 26, No. 7, pp. 950-957 (Jul. 1983).
McClure, David E., et al., "Antihypertensive .beta.-Adrenergic Blocking Agents: N-Aralkyl Analogues of 2-[3-(tert-Butylamino)-2-hydroxypropoxy]-3-cyanopyridine.sup.1 ", Journal of Medicinal Chemistry, vol. 26, No. 5, pp. 649-657 (May 1983).
Large, M. S., et al., ".beta.-Adrenergic Blocking Agents. 23. 1-[(Substituted-amido)phenoxy]-3-[[(substituted-amido)alkyl]amino]propan-2 -ols", Journal of Medicinal Chemistry, vol. 26, No. 3, pp. 352-357 (Mar. 1983).
Rouot, Bruno, et al., "Clonidine and Related Analogues. Quantitative Correlations" Journal of Medicinal Chemistry, vol. 19, pp. 1049-1054 (1976).
Timmermans, et al., "Structure-Activity Relationships in Clonidine-Like Imidazolidines and Related Compounds", published in 1980 by Gustav Fischer Verlag, of Stuttgart and New York, pp. 1-97.
Gan Owen
Jani Rajni
Lorenzetti Ole J.
Alcon Laboratories Inc.
Brown Gregg C.
Killos Paul J.
Yeager Sally
LandOfFree
Intraocular irrigating solution containing agent for controlling does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Intraocular irrigating solution containing agent for controlling, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intraocular irrigating solution containing agent for controlling will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-383626