Intranasal administration of Mycoplasma hyopneumoniae antigen

Details Intranasal administration of Mycoplasma hyopneumoniae antigen Intranasal administration of Mycoplasma hyopneumoniae antigen

1989-04-07

1993-08-31

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 435 691, 435 693, 435 711, 4351721, 4351723, 435870, 935 12, 935 31, 935 65, 935 81, 530350, 530806, 530820, 530821, A61K 3902, C12P 2106

Patent

active

052407063

ABSTRACT:
A method for protecting an animal, in particular swine, against mycoplasma pneumonia by administering intranasally to the animal a vaccine containing one or more proteins which elicits an antibody which recognizes a Mycoplasma hyopneumoniae antigen which lacks immunosuppressive activity. A particularly preferred intranasal vaccine includes the 74.5 kDa antigen of Mycoplasma hyopneumoniae. The 74.5 kDa antigen may be of recombinant origin.

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Klinkert et al., Chemical Abstracts, vol. 103, Reference #103070x, 1985.
Tajuna et al., Biological Abstracts, vol. 79, Reference #31582, 1984.
Jacobs et al., Chemical Abstracts, vol. 108, Reference #148536y, 1988.

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