Intramolecularly cross-linked hemoglobin and method of preparati

Details Intramolecularly cross-linked hemoglobin and method of preparati Intramolecularly cross-linked hemoglobin and method of preparati

1985-03-29

1986-04-22

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 260115, 424101, 514 6, C07C10352, A61K 3518, A61K 3702, C07K 1300

Patent

active

045841306

ABSTRACT:
Stroma-free hemoglobin cross-linked with reagents that mimic 2,3 diphosphoglycerate and transform stroma-free hemoglobin into a physiologically competent oxygen carrier which is retained in vivo for adequate periods of time and thus can be used in fluids for transporting oxygen; reagents for cross-linking stroma-free hemoglobin and method for cross-linking stroma-free hemoglobin.

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