Intracellularly cleavable compounds

Details Intracellularly cleavable compounds Intracellularly cleavable compounds

1990-05-14

1992-12-08

Cashion, Jr., Merrell C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

11 to 14 amino acid residues in defined sequence

5303919, 514 14, 514 2, 424 9, A61K 3710, A61K 3702, A61K 3100, A61K 4900

Patent

active

051699346

ABSTRACT:
Intracellularly cleavable derivatives of toxic compounds including antibiotics are described.

REFERENCES:
patent: 4460560 (1984-07-01), Tokes et al.
patent: 4839175 (1989-06-01), Guo et al.
patent: 4847240 (1989-07-01), Ryser et al.
patent: 4861581 (1989-08-01), Epstein et al.
patent: 4871528 (1989-10-01), Tongella et al.
patent: 4873088 (1989-10-01), Mayhew et al.
Blair et al., J. of Immun. Methods, vol. 59, pp. 129-143, (1983).
Shen et al., Biochem. Biophys. Res. Comm., vol. 102, No. 3, pp. 1048-1054, 1981.
Blattler et al., Biochemistry, vol. 24, pp. 1517-1524, 1985.

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