Intra-pocket drug delivery devices for treatment of periodontal

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424443, 424444, 432 80, A01N 1800

Patent

active

047643773

ABSTRACT:
Therapeutic agent delivery devices and methods for using them in treatment of dental disease are disclosed. In the treatment of periodontal disease, a therapeutic agent such as tetracycline mixed in a polymeric matrix such as ethylene vinyl acetate copolymer is packed into the area to be treated and kept in place for a suitable time, during which the therapeutic agent diffuses out of the polymeric matrix, providing continuous therapy for the treatment site.

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J. M. Goodson et al, "Monolithic Tetracycline-Containing Fibers for Controlled Delivery to Periodontal Pockets", J. Periodontology, 54, pp. 575-579 (1983).
Exerpts from "The Polymer Handbook", 2nd Edition, J. Brandrup and E. H. Immergut, Editors, John Wiley & Sons (1975).
Computer printouts concerning patents referred to in, or citing, U.S. Pat. Nos. 4,024,871 by Stephenson and 3,849,185 by Shepherd.

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