Intestinal trefoil proteins

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

530300, 530324, 530350, A01N 3718, A61K 3800

Patent

active

060637552

ABSTRACT:
Intestinal trefoil factors and nucleic acids encoding intestinal trefoil factors are disclosed. The intestinal trefoil factors disclosed are resistent to destruction in the digestive tract and can be used for the treatment of peptic ulcer diseases, inflammatory bowel diseases and other insults.

REFERENCES:
Suemori et al., "Identification and characterization of rat intestinal trefoil factor: Tissue- and cell-specific . . . ", Proc. Natl. Acad. Sci., 88:11017-11021 (1991).
Parson, J.A. (Editor) "Peptide Hormones", published by University Park Press see Chapter 1, pp 1-7 by Rudinger, Jun. 1976.
Lazar et al. Mol. Cell. Biology 8(3):1247-52, Mar. 1988.
Burgess et al. J. Cell Biol. 111:2129-38, Nov. 1990.
Babyatsky, M.W. et al. Gastroenterology, vol. 106, No. 4, p. A43 (abstract), Apr. 1994.
Maniatis, T., et al. 1982, Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Habor, New York, pp. 224-246, 270-307, 310-352, 404-433.
Jorgensen, K.D., et al., 1982, Pancreatic Spasmolytic Polypeptide (PSP): III. Pharmacology of a new porcine pancreatic polypeptide with spasmolytic and gastric acid secretion inhibitory effects, Reg.Pep. 3:231-243.
Thim, L., et al., 1982, Pancreatic Spasmolytic Polypeptide (PSP): II. Radioimmunological determination of PSP in porcine tissues, plasma and pancreatic juice, Regulatory Peptides, 3:221-230.
Jorgensen, K.H., et al., 1982, Pancreatic Spasmolytic Polypeptide (PSP): I. Preparation and initial chemical characterization of a new polypeptide from porcine pancreas, Regulatory Peptides, 3:207-219.
Jakowlew, S.B., et al., 1984, Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7, 12:2861-2878.
Frandsen, E.K., et al., 1986, Receptor binding of pancreatic spasmolytic polypeptide (PSP) in rat intestinal mucosal cell membranes inhibits the adenylate cyclase activity, Regulatory Peptides, 16:291-297.
Rio, M.C., et al., 1988, Breast Cancer-Associated pS2 Protein: Synthesis and Secretion by Normal Stomach Mucosa, Science, 241:705-708.
Podolsky, D.K., et al., 1988, Latent Transformed Growth-inhibiting Factor in Human Malignant Effusions, Cancer Research, 48:418-424.

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