Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1978-08-30
1980-09-30
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548186, 548187, C07D27704
Patent
active
042256097
ABSTRACT:
This invention relates to novel interphenylene 9-thia-11-oxo-12-azaprostanoic acid compounds, salts, and derivatives thereof. These compounds are exceptionally potent renal vasodilators and antihypertensives which are active when administered orally but which have a more specific type of biological activity than that of many of the natural prostaglandins and their synthetic analogs or derivatives.
REFERENCES:
patent: 3881017 (1975-04-01), Vlattas
patent: 3883659 (1975-05-01), Vlattas
patent: 4022794 (1977-05-01), Smith et al.
Morton et al, Abstract of Paper, 172nd ACS National Meeting, Aug. 30-Sep. 3, 1976, Chemical Society Division of Medicinal Chemistry.
Ambros et al, Prostaglandins, vol. 10, pp. 661-666, (1975).
Bicking John B.
Cragoe, Jr. Edward J.
Lee Ta-jyh
Anderson, Jr. Rudolph J.
Arther Thomas E.
Merck & Co. , Inc.
Monaco Mario A.
Rizzo Nicholas S.
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