Intermediates useful in a process for the preparation of azanora

Details Intermediates useful in a process for the preparation of azanora Intermediates useful in a process for the preparation of azanora

1995-05-19

1996-07-30

Trinh, Ba Kim

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549304, 549305, 549311, C07D30793

Patent

active

055413447

ABSTRACT:
The present invention is directed to intermediates of the formula ##STR1## which are useful in a process for the preparation of aminoazanoradamanatanes.

REFERENCES:
patent: 5140023 (1992-08-01), Becker et al.
patent: 5223613 (1993-06-01), Becker et al.
Use of Atom-Transfer Radical Cyclizations as an Efficient Entry into a New "Serotonergic" Azanoradamantane, Tetrahedron Letters, vol. 33, No. 48, 1992 Oxford GB, pp. 7283-7286.
Ozone Cleavage of Olefins with Formation of Ester Fragments, Angewandte Chemie International Edition, , vol. 17, No. 12, 1978 Weinheim De, pp. 939-940.
Abstract-- Database WPI, Derwent Publications Ltd., London, GB; AN 92-069451 and JP, A, 04 013 663 (Sumitomo Seiyaku KK), Jan. 17, 1992.
"New AZA(NOR) Adamantanes are Agonists at the Newly Identified Serotonin 5-HT4 Receptor and Antagonists at the 5-HT3 Receptor" Bioorganic & Medicinal Chemistry Letters, vol. 2, No. 12, pp. 1613-1618, 1992.
"Building Blocks for the Synthesis of Enantiomerically Pure Jasmonoids: Synthesis of (+)--Methyl Epijasmonate**" Angew. Chem. Int. Ed. Engl. 29, (1990) No. 9, pp. 1024-1025.
"High Steroselectivity in Lewis-Acid-Catalyzed and Uncatalyzed Diels-Alder Reactions of the Fumarate of (S) Ethyl Lactate**" Angew. Chem. Int. Ed. Engl. 26, (1987), No. 11, pp. 1143-1145.
"Asymmetric Diels-Alder Reactions with Chiral Enoates as Dienophiles", Modern Synthetic Methods, 1986, vol. 4, pp. 263-306.

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