Intermediates to 1-carbacephalosporins and process for preparati

Details Intermediates to 1-carbacephalosporins and process for preparati Intermediates to 1-carbacephalosporins and process for preparati

1991-07-25

1992-10-27

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

549493, C07D20585, C07D40506, C07D30754, C70B 3502

Patent

active

051590735

ABSTRACT:
Disclosed is a process using hydrolysis and hydrogenation for converting enamino .beta.-lactams to their saturated alkyl ester acid salts, key intermediates to 1-carbacephalosporins. Also disclosed are intermediates resulting from the process.

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Hirai, Chemical Abstract, vol. 106, No. 5, p. 519, col. 1, 32 729t.
Minoru Hatanaka and Toshiyasu Ishimaru, "A Simple Synthesis of (.+-.)-1-Carbacephem Derivatives", Tetrahedron Letters, vol. 24, No. 44, pp. 4837-4838 (1983).

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