Intermediates in the production beta aminoalcohols

Details Intermediates in the production beta aminoalcohols Intermediates in the production beta aminoalcohols

1995-03-09

1996-05-14

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C22934

Patent

active

055169309

ABSTRACT:
Acid esters of formula, ##STR1## wherein R2 is lower-alkyl, or acid-addition salts thereof useful as intermediates in the production of beta-aminoalcohols.

REFERENCES:
patent: 4374829 (1983-02-01), Harris et al.
patent: 5157041 (1992-10-01), Handa et al.
patent: 5236783 (1993-10-01), Gokhale et al.
Burkhart et al, Tetrahedron Letters, vol. 29, No. 28, 1988, pp. 3433-3436.
Kobayashi et al., Tetrahedron Letters, vol. 31, No. 21, 1990, pp. 3031-3034.
Melon, et al, Enantiomerically pure 3-amino-2-hydroxy and 5-amino-4-hydroxy acids from D-isoascorbic acid, Bull Soc. Chim Fr, vol. 129, pp. 585-593 (1992).
Iizuka, et al, Orally Potent Human Renin Inhibitors Derived from Angiotensinogen Transition State: Design, Synthesis, and Mode of Interaction, J. Med. Chem. vol. 33, pp. 2707-2714 (1990).

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