Intermediates in the preparation of substituted alkenoic acids

Details Intermediates in the preparation of substituted alkenoic acids Intermediates in the preparation of substituted alkenoic acids

1998-09-10

2000-02-29

Fan, Jane

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

546209, 546 14, 548237, C07D41312

Patent

active

060310952

ABSTRACT:
This invention relates to a highly selective process for preparation of E-.omega.-phenyl-.omega.-(3-pyridyl)-.omega.-alkenoic acid derivatives bearing a carbamoyl substituted oxazolyl or oxazolinyl group on the phenyl ring which demonstrate utility for thromboxane receptor antagonism and/or thromboxane synthase inhibition, as well as to intermediates therefor.

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