Intermediates for the resolution of some interphenylene-9-thia-1

Details Intermediates for the resolution of some interphenylene-9-thia-1 Intermediates for the resolution of some interphenylene-9-thia-1

1981-06-22

1983-06-28

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548186, C07D27704

Patent

active

043907032

ABSTRACT:
Some derivatives of interphenylene-9-thia-11-oxo-12-azaprostanoic acid which are active renal vasodilator agents are resolved via diastereomeric camphanyl or camphorcarbonyl esters. Upon hydrolysis, the separated diastereoisomers yield optically pure enantiomers.

REFERENCES:
patent: 4225609 (1980-09-01), Cragoe, Jr. et al.
B. Halpern et al., Chem. Abstracts 65:19996(e), (1966).
Gerlach, Helv. Chem. Acta, 1987-1593, (1969), English Translation.

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