Intermediates for the preparation of tetrahydroisoquino[2,1-c][1

Details Intermediates for the preparation of tetrahydroisoquino[2,1-c][1 Intermediates for the preparation of tetrahydroisoquino[2,1-c][1

1989-12-21

1990-10-16

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540555, 546149, C07D21718

Patent

active

049636855

ABSTRACT:
Novel Tetrahydroisoquino[2,1-c][1,3]benzodiazepines are disclosed having the formula ##STR1## where X and Y are each independently hydrogen, halogen, loweralkyl, loweralkoxy or --CF.sub.3, and R is hydrogen or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility in enhancing memory.

REFERENCES:
patent: 3153043 (1964-10-01), Weisbach
patent: 4053603 (1977-10-01), Neumeyer et al.
Ochiai, et al., "Chemical Abstracts", vol. 52, 1958, col. 14605e.
Dalton, et al., "Chemical Abstracts", vol. 77, 1972, col. 152407r.

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