Intermediates for the preparation of heteroaryl derivatives of m

Details Intermediates for the preparation of heteroaryl derivatives of m Intermediates for the preparation of heteroaryl derivatives of m

1993-11-29

1995-05-30

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544229, 544337, 544354, 544355, 560160, 564443, C07D24144, C07D49104

Patent

active

054202779

ABSTRACT:
Antibacterial activity is exhibited by novel compounds having the formula ##STR1## where R.sub.1, R.sub.2, and M are as defined herein and X is --(CH.sub.2).sub.n -- wherein n is 0, 1, 2, 3 or 4 or CR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 are the same or different and each is hydrogen, --CH.sub.3 or --C.sub.2 H.sub.5 or R.sub.3 and R.sub.4 taken together with the carbon atom to which they are attached form a 3, 4, 5, 6 or 7-membered cycloalkyl ring. Also described are various intermediates for the preparation of compounds of formula 1.

REFERENCES:
patent: 5037983 (1991-08-01), Sundeen et al.
patent: 5250691 (1993-10-01), Straub et al.
patent: 5290929 (1994-03-01), Koster et al.
Koster et al, Chemical Abstracts, vol. 117, No. 90045 (Abstract for EP484881, May, 13 1992) (1993).
Budesinsky et al, Collection Czechoslov. Chem. Commun. 36, pp. 2527-2539 (1971).

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