Intermediates for the preparation of cyclic urea

Details Intermediates for the preparation of cyclic urea Intermediates for the preparation of cyclic urea

1994-06-30

1995-11-14

Gupta, Yogendra N.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540502, C07D24304

Patent

active

054667976

ABSTRACT:
This invention relates to novel compounds and derivatives thereof containing a trioxepane protected diol in addition to a hydrazone, hydrazine, amine, or cyclic urea moiety; methods for the preparation of said compounds; and the use of said compounds in processes to prepare human immunodeficiency virus (HIV) protease inhibitors which effectively inhibit HIV. The novel compounds provided by this invention have the formulae: ##STR1## wherein the substituents are as defined herein.

REFERENCES:
Baker and Condon, J. Org. Chem. 58, 3277-3284 (1993).
Seebach, D. et al., Chimia, 45 (7/8) 238-244 (1991).

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