Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1986-02-14
1987-09-29
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
540579, 544349, 544384, A61K24118, A61K47104, A61K48704, A61K48714
Patent
active
046970169
ABSTRACT:
The invention relates to a novel process for the preparation of the optically pure 2S- or 2R-indolinecarboxylic acid of the formula ##STR1## and salts thereof. The process comprises forming the heterocyclic 5-membered ring in formula I from an open chain precursor by diastereoselective cyclization.
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Gschwend Heinz W.
Roloff Achim
Berch Mark L.
Ciba-Geigy Corporation
Gruenfeld Norbert
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