Intermediates for synthesis of vitamin D derivatives

Details Intermediates for synthesis of vitamin D derivatives Intermediates for synthesis of vitamin D derivatives

2004-02-18

2009-10-06

Davis, Brian J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C556S012000

Reexamination Certificate

active

07598408

ABSTRACT:
The present invention provides a novel intermediate for synthesizing vitamin D derivatives by using a less expensive material. That is, the present invention provides a compound which is synthesized by using carvone as a starting material and which is represented by the following formulae.

REFERENCES:
patent: 5086191 (1992-02-01), De Luca et al.
patent: 5536713 (1996-07-01), De Luca et al.
patent: 5886233 (1999-03-01), Steinmeyer et al.
patent: 20250844 (1990-10-01), None
patent: 5-186421 (1993-07-01), None
patent: 10-502061 (1998-02-01), None
patent: 2001-504135 (2001-03-01), None
patent: 98/41501 (1998-09-01), None
patent: 00/10548 (2000-03-01), None
patent: 01/03704 (2001-01-01), None
patent: WO0118003 (2001-03-01), None
patent: 01/72292 (2001-10-01), None
patent: 01/74765 (2001-10-01), None
patent: 01/74766 (2001-10-01), None
patent: 01/92221 (2001-12-01), None
patent: 02/05823 (2002-01-01), None
patent: 02/05824 (2002-01-01), None
patent: 02/20021 (2002-03-01), None
Kirsch et al (Synthesis 2003, No. 12, 1827-1836).
Hilpert et al (Tetrahedron 57 (2001) 681-694).
Wang et al (J. Org. Chem. 1998, 63, 3051-3058).
Parker et al (Journal of Organic Chemistry (1997), 62(19), 6692-6696).
Rücker, G. et al., “Stereoselective Reduction of Cyclic 2,3-Epoxyketones to Trans-2,3-Epoxyalcohols”,Synthetic Communications, vol. 10, No. 8, pp. 623 to 626 (1980).
Barbier, P. et al., “Efficient Fluorination with Tetrabutylammonium Dihydrogen Trifluoride in a Novel Approach toward 1-α-Fluoro-25-hydroxy-vitamin D3Analogues”,Journal of Organic Chemistry, vol. 63, No. 20, pp. 6984 to 6989 (1998).
Wang, J. et al., “Enantioselective Approach to the Synthesis of Cyclohexane Carbocyclic Nucleosides”,Journal of Organic Chemistry, vol. 163, No. 9, pp. 3051 to 3058 (1998).
Hatakeyama, S. et al., “Efficient enantio specific synthesis of key-A-ring synthons for the preparation of 1α, 25-dihydroxyvitamin D3 using a chromium(II)-mediated reaction”,Journal of Organic Chemistry, vol. 54, No. 15, pp. 3515 to 3517 (1989).
Knoelker, H. et al., Enantioselective synthesis of calcitriol A-ring fragments,Tetrahedron, vol. 53, No. 1, pp. 91 to 108 (1997).

Affiliated with

Also associated with

Rating

Intermediates for synthesis of vitamin D derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intermediates for synthesis of vitamin D derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intermediates for synthesis of vitamin D derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4099679