Intermediates for synthesis of tetramisole, levamisole and their

Details Intermediates for synthesis of tetramisole, levamisole and their Intermediates for synthesis of tetramisole, levamisole and their

1976-11-08

1978-05-16

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2603067T, 260307F, 2605705C, C07D23332, C07D23338, C07D23342

Patent

active

040900258

ABSTRACT:
A process for the manufacture of 1-(2-alkoxyethyl)-4-phenyl-4-imidazolin-2-ones, 1-(2-alkoxyethyl)-4-phenyl-2-imidazolidones, 1-(2-alkoxyethyl)-4-phenyl-imidazolidine-2-thiones, certain of the corresponding 1-(2-hydroxyethyl) derivatives and their 3-acylated derivatives, and certain related compounds which are all useful as intermediates in a new process for the manufacture of tetramisole, dl-2,3,5,6-tetrahydro-6-phenylimidazo-[2,1-b]thiazole, and its derivatives. The compound tetramisole is useful as an anthelmintic.

REFERENCES:
patent: 3726894 (1973-04-01), Spicer
Fieser et al. Advanced Organic Chemistry pp. 73-78, N.Y. Reinhold, 1961.
Rodionov et al. Chem. Abst. 1949, vol. 43, Column 3821.
Kametani Chem. Abst. 1952, vol. 46, columns 4547-4548.

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