Intermediates for spiro[2H-1,4 benzodioxepin-3(5H)4'-piperidine

Details Intermediates for spiro[2H-1,4 benzodioxepin-3(5H)4'-piperidine Intermediates for spiro[2H-1,4 benzodioxepin-3(5H)4'-piperidine

1985-12-19

1987-09-22

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40904

Patent

active

046956379

ABSTRACT:
Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.

REFERENCES:
patent: 3966758 (1976-06-01), Schwan et al.
Mailey et al., "J. Org. Chem.", vol. 22, pp. 1061-1065, (1957).
Fieser and Fieser, "Reagents for Organic Synthesis", vol. 2, pp.182-187, (1969); ibid., vol. 3, pp. 135-136, (1972).

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