Intermediates for prostaglandin synthesis

Details Intermediates for prostaglandin synthesis Intermediates for prostaglandin synthesis

1977-02-22

1979-04-24

Sneed, Helem M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603459P, 2603478, 2604381, 424305, 560121, 542426, 542413, C07F 722

Patent

active

041511875

ABSTRACT:
Compounds of the formula ##STR1## wherein R is phenyl cyclohexyl or lower alkyl containing 1-6 carbon atoms; R" is hydrogen or methyl; R'" is alkenyl or alkynyl having 3-5 carbon atoms; R' is hydrogen, tetrahydrofuran-2-yl tetrahydropyran-2-yl or trialkylsilyl wherein the alkyl contains 1-4 carbon atoms. Compounds of the present invention are useful in synthesizing prostaglandin like molecules which are active anti-secretory agents.

REFERENCES:
patent: 4038308 (1977-07-01), Strike
patent: 4061670 (1977-12-01), Floyd et al.
Corey et al., JACS 98 (1), pp. 222-224 (1976).
Chemical Abstracts 82 1254452y (1975).
Chemical Abstracts 84 31199k (1976).
J. Organometallic Chem. 109, 267, 288, 328, (1976).
J. Organometallic Chem. 53, 30-32, (1973).

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