Intermediates for preparing peptide boronic acid inhibitors of t

Details Intermediates for preparing peptide boronic acid inhibitors of t Intermediates for preparing peptide boronic acid inhibitors of t

1992-03-09

1993-10-05

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Borate esters

558289, C07F 504

Patent

active

052507203

ABSTRACT:
Intermediates for the preparation of Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.

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