Intermediates for preparing HMG-CoA reductase inhibitors

Details Intermediates for preparing HMG-CoA reductase inhibitors Intermediates for preparing HMG-CoA reductase inhibitors

1988-08-12

1989-10-17

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 6, 544 584, 544 70, 544139, 544230, 544370, 546 15, 546199, 546206, 548327, 548333, 548341, C07D40510

Patent

active

048748706

ABSTRACT:
A process for converting 6-carboxy to 6-hydroxymethyl mevinolin analogs and novel intermediates formed in this process are disclosed.

REFERENCES:
H. Staab, Angew. Chem. Internat. Edit., 1,351 (1962).
K. Ishizumi, et al., Chem. Pharm. Bull., 16(3), 492 (1968).
Hajos, Complex Metal Hydrides, Elsevier Scientific Publishers, New York, 1979, pp. 49-55 and 333-337.

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